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In one study, about a third of people lost more than 5% of their body weight, another third didnt lose much, and another third actually gained weight
As a general rule, we dont recommend surgery to prevent trouble from gallstones
If you become pregnant while on semaglutide, contact your provider right away
Important cautions include avoiding use in patients with severe gastroparesis or other severe gastrointestinal disease, monitoring for diabetic retinopathy complications (particularly in patients with pre-existing retinopathy), and avoiding use during pregnancy with a recommended washout period of at least 2 months before planned conception
On the other hand, it has also been observed that patients with obesity have a chronic inflammatory state of low grade (59)
Compounding these risks is the fact that long-term effects remain largely unknown, as millions of people are still in the early stages of taking these medications
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